首页|Discrimination of pharmacodynamic components and volatile compounds of Poria cocos cultivated with five different materials based on GC-IMS analysis

Discrimination of pharmacodynamic components and volatile compounds of Poria cocos cultivated with five different materials based on GC-IMS analysis

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Objectives:The chemical constituents of Poria cocos grown with different substrates vary significantly;thus,identifying and comparing their biomarkers are important.Materials and Methods:Herein,the chemical constituents of Poria cocos obtained with five different substrates were assessed using gas chromatography-ion mobility spectrometry(GC-IMS),high-performance liquid chromatography and multivariate statistical analysis.Results:The content of moisture,ash,alcohol-soluble matter,and heavy metals,except for those of the miscellaneous wood Poria cocos,conform to the specifications defined in the Chinese Pharmacopoeia(Edition 2020),and the polysaccharide contents are all greater than 57％.Conclusions:Based on GC-IMS and the established fingerprints,87 compounds were detected,70 of which were identified in each group.Multivariate statistical analysis revealed seven compounds(two esters,three alcohols,and two aldehydes),which could be considered as po-tential marker compounds for discrimination.

Poria cocos,cultivation materialpharmacodynamic componentgas chromatography-ion mobility spectrometry(GC-IMS)volatile compound

Yinan Wang、Fei Zhou、Hui Wang、Jinping Zhang、Hongxia Xu

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Research Institute of Subtropical Forestry,Chinese Academy of Forestry,Hangzhou,China

Chun'an County Thousand-island Lake Forest Farm,Hangzhou,China

National Key Research and Development Program of ChinaWorld Bank Loans Qiandao Lake and Xin'an River Basin Water Resources and Ecological Protection Projects in Zhejiang,China

2023YFD2200903CLJY3

2024

10.1093/fqsafe/fyad058

食品品质与安全研究(英文版)

食品品质与安全研究(英文版)

ISSN：
年,卷(期)：2024.8(1)
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