两种基于三苯胺衍生物的合成及性质研究
Synthesis and properties of two triphenylamine derivatives
王亚轩 1黄娜 1杜海灵 1王志宇 1胡磊 1王慧1
作者信息
- 1. 皖南医学院药学院,安徽芜湖 241002
- 折叠
摘要
以三苯胺为母体,设计合成了两种三苯胺衍生物L1和L2,其结构经核磁共振氢谱和红外光谱仪表征.研究了两种化合物在不同体积比的乙醇/水混合溶剂中的紫外可见吸收光谱和荧光发射光谱.结果表明:化合物L1具有明显的聚集诱导发光(AlE)性质,而化合物L2则展现双态发射(DSE)性质.细胞实验结果表明,这两种化合物均具有较低的细胞毒性,能够穿透细胞膜,着色细胞的细胞质区域,而且化合物L2的成像效果较好.
Abstract
In this paper,two triphenylamine derivatives L1 and L2 were designed and synthesized with triphenylamine as raw materials,and their structures were characterized by 1H NMR and IR spectroscopy.UV-vis absorption and fluorescence emission spectra of these two complexes in ethanol-water mixture with different fraction of water were investigated.The results showed that L1 exhibited obvious an aggregation-induced emission(AIE)property,while L2 exhibited a dual-state emission(DSE)property.Cell experiments have shown that both compounds have low cytotoxicity and are capable of penetrating the cell membranes and staining cytoplasmic regions of cells,with compound L2 performing better imaging.
关键词
聚集诱导发光/双态发射/三苯胺/细胞成像Key words
aggregation-induced emission/double-state emission/triphenylamine/cell imaging引用本文复制引用
出版年
2024
NETL
NSTL
万方数据