Nazarov反应构建手性环戊烯酮的研究进展
Research progress on the construction of chiral cyclopentenone by Nazarov reaction
陈致州1
作者信息
- 1. 闽江师范高等专科学校智能制造学院,福建 福州 350001;闽江师范高等专科学校双碳智慧能源技术研究中心,福建 福州 350001
- 折叠
摘要
Nazarov反应大多为酸催化下二乙烯基酮重排成环戊烯酮.手性环戊烯酮因具有独特的结构和多样化的反应位点活性而一直备受有机合成工作者的关注.近几年业界鲜有对此类反应进行综述,为了让从业者们更加透彻了解该研究方向的最新进展,将分为Lewis酸催化、Brønsted酸催化和其他类型条件三大种类归纳总结2018-2022年以来Nazzarov反应构建手性环戊烯酮的报道,并展望未来研究方向,对进一步研究该类型反应具有重要意义.
Abstract
Nazarov reaction is acid-catalyzed rearrangement of divinyl ketone into cyclopentenone.Chiral cyclopentenone has been attracting the attention of organic synthesis practitioners due to its unique structure and diverse reaction site activity.Considering that there have been few reviews of such reactions recently and in order to allow practitioners to have a more thorough understanding of the progress of this research direction,this article will summarize the reports of Nazzarov reaction to construct chiral cyclopentenone in the past five years,which are divided into three categories:Lewis acid catalysis,Brønsted acid catalysis and other types of conditions.Further research directions will be prospected,which is of great significance for development and research of Nazarov reaction.
关键词
Nazarov反应/二乙烯基酮/手性环戊烯酮/路易斯酸/布朗斯特酸Key words
Nazarov reaction/divinyl ketone/chiral cyclopentenone/Lewis acid/Brønster acid引用本文复制引用
出版年
2024
NETL
NSTL
万方数据