首页|Efficacy and moderating factors of the Early Start Denver Model in Chinese toddlers with autism spectrum disorder:a longitudinal study

Efficacy and moderating factors of the Early Start Denver Model in Chinese toddlers with autism spectrum disorder:a longitudinal study

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
  • 维普
Background Several studies have shown the effectiveness of the Early Start Denver Model(ESDM),but few studies have explored the long-term efficacy of ESDM.This study aimed to explore the efficacy and moderating factors of ESDM in Chinese toddlers with autism spectrum disorder(ASD)in a longitudinal way.Methods A total of 60 toddlers with ASD were recruited and randomly divided into two groups:ESDM group all received 24 weeks intervention;Control group were waiting for intervention.Baseline assessment(T0)was conducted before interven-tion,including Gesell Developmental Scale(GDS)and Psycho-educational Profile-3rd Edition(PEP-3).All toddlers with ASD were examined in the first assessment(T1)at 6 months and in the second assessment(T2)at 12 months.Results In T1 assessment,the increments in speech and personal communication development quotient in GDS were sig-nificantly larger in the ESDM group than in the control group(P=0.010,0.047).In T2 assessment,the ESDM group had higher elevation in cognitive verbal/preverbal(CVP),social reciprocity and characteristic verbal behaviors assessed by PEP-3(P=0.021,0.046,0.014).In addition,the severity of stereotyped behavior was negatively associated with improvement in CVP.Family income was positively associated with improvement in speech and CVP(all P＜0.05).Conclusions ESDM can effectively improve speech and communication in toddlers with ASD after 24-week intervention.More importantly,ESDM can promote cognition and social interaction and can reduce stereotyped verbal behavior in toddlers with ASD in longitudinal observation.The severity of stereotyped behavior and family ecological factors may be considered as affecting the efficacy of ESDM.

Autism spectrum disorderEfficacyEarly Start Denver ModelLongitudinalModerating factorsStereotyped behavior

Shi-Huan Wang、Hai-Tao Zhang、Yuan-Yuan Zou、San-Mei Cheng、Xiao-Bing Zou、Kai-Yun Chen

展开 >

Child Developmental and Behavioral Center,The Third Affiliated Hospital of Sun Yat-sen University,No.600,Tianhe Road,Guangzhou 510630,China

Scientific Research project of National Health CommissionNational Natural Science Foundation of ChinaTechnology Program of Guangzhou,ChinaScience and Technology Program of Guangzhou

20130200281873801201903010040202007030011

2023

10.1007/s12519-022-00555-z

世界儿科杂志(英文版)

世界儿科杂志(英文版)

CSTPCDCSCD
ISSN：
年,卷(期)：2023.19(8)
  • 1
  • 34