首页|Differentiating rhythmic high-amplitude delta with superimposed(poly)spikes from extreme delta brushes:limitations of standardized nomenclature and implications for patient management
Differentiating rhythmic high-amplitude delta with superimposed(poly)spikes from extreme delta brushes:limitations of standardized nomenclature and implications for patient management
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Background Following the standardized nomenclature proposed by the American Clinical Neurophysiology Society(ACNS),rhythmic high-amplitude delta activity with superimposed spikes(RHADS)can be reported as an extreme delta brush(EDB).The clinical implications of similar electrographic patterns being reported as RHADS versus EDB are important to highlight.We aim to review the electrographic characteristics of RHADS,evaluate whether RHADS is seen in other neurological disorders,and identify the similar and unique characteristics between RHADS and EDB to ultimately determine the most accurate way to differentiate and report these patterns.We believe that the differentiation of RHADS and EDB is important as there is a vast difference in the diagnostic approach and the medical management of associated underlying etiologies.Data source We conducted an extensive search on MEDLINE and Pubmed utilizing various combinations of keywords.Searching for"gamma polymerase and EEG",or"RHADS"or"Alpers syndrome and EEG"or"EEG"AND"Alpers-Hut-tenlocher syndrome".Results Three articles were found to be focused on the description of"RHADS"pattern in Alpers Syndrome.No publica-tion to date were found when searching for the terms"EDB"AND"children",AND"infant"AND"adolescent"excluding"encephalitis"and"neonate".Although RHADS and EDB appear as similar EEG patterns,meticulous analysis can differ-entiate them.RHADS is not exclusive to patients with Alpers-Huttenlocher syndrome and may manifest in regions beyond the posterior head region.Reactivity to eye-opening and response to anesthesia can be two other elements that help in the differentiation of these patterns.Conclusion RHADS is not exclusive to patients with AHS and may manifest in regions beyond the posterior head region.Reactivity to eye-opening and response to anesthesia are features that help in the differentiation of these patterns.
NETL
NSTL
万方数据
