首页|Human mpox co-infection with advanced HIV-1 and XDR-TB in a MSM patient previously vaccinated against smallpox:A case report

Human mpox co-infection with advanced HIV-1 and XDR-TB in a MSM patient previously vaccinated against smallpox:A case report

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Mpox is a zoonotic infectious disease caused by the mpox virus(MPXV).Historically,the majority of mpox cases have been documented in Central Africa.However,since May 2022,there has been a notable rise in reported cases from regions beyond Africa.Currently,over 110 countries spanning Europe,North America,South America,Asia,and other territories have reported mpox infections.This report details a case involving a patient who identifies as a man who has sex with men(MSM)and is concurrently infected with MPXV,human immunodeficiency virus type 1(HIV-1),Pneumocystis jiroveci,as well as extensively drug-resistant tuberculosis(XDR-TB).This patient had also received a vaccination for smallpox in the past.Additionally,we provide pho-tographic documentation charting the progression of dermatological manifestations associated with mpox.This case highlights the significance of sexual intercourse as a crucial mode of transmission for mpox.The rapid and widespread dissemination of the MPXV across various regions,especially among MSM communities,under-scores the importance of enhancing preventive education efforts targeted at high-risk populations.

MpoxMpox virus(MPXV)Human immunodeficiency virus type 1(HIV-1)Extensively drug-resistant tuberculosis(XDR-TB)

Yuan Fang、Fuchun Wang、Taiyi Jiang、Junyi Duan、Tao Huang、Hao Liu、Lin Jia、Han Jia、Benyong Yan、Mei Zhang、Wen Wang、Caiping Guo、Lifeng Liu、Yuening Zhang、Tong Zhang

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Beijing Youan Hospital,Capital Medical University,Beijing 100069,China

National Natural Science Foundation of ChinaNational Natural Science Foundation of China

8224106882241072

2024

生物安全与健康 (英文)
中华医学会

生物安全与健康 (英文)

CSTPCD
ISSN:2096-6962
年,卷(期):2024.6(3)