首页|An online survey among convalescents 5 months post SARS-CoV-2 infection in China
An online survey among convalescents 5 months post SARS-CoV-2 infection in China
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The effects of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection persist months and years after recovery.We conducted an online survey to assess the health condition of convalescents approxi-mately 5 months following the primary infection of SARS-CoV-2.The study recruited 5,510 individuals who were primary infected,626 participants who had experienced reinfection,and 521 participants who were with-out infective history.The most common disorders after the primary infection group were fatigue(15.18％),memory issue(13.13％),post-exertional malaise(PEM,11.68％),and brain fog(11.29％)at the time of sur-vey.In addition,SARS-CoV-2 infection had an impact on the reproductive systems.In stepwise logistic regres-sion analysis,smoking currently,with background diseases,and outpatient visits in the acute phase could be associated with moderate/severe disorders.Further analysis of different background diseases showed that allergic rhinitis,hyperlipidemia,cardiovascular disease,autoimmune diseases,neurological diseases,and asthma likely increased the risk of moderate/severe disorders.The probability of developing disorders of indi-viduals with SARS-CoV-2 reinfection was higher before the secondary infection than uninfected people.Fatigue,PEM,muscle pain/spasms,chills,joint pain,excessive sweating at rest,headache/dizziness,sore throat or foreign body sensation in the throat,cough,expectoration,dry/painful/watery eyes,loss of appetite and constipation were associated with an increased risk of reinfection.It was essential to undertake further research with enhanced randomization in a larger sample in the community,and to strengthen the validation of the research conclusions.The findings of this study contribute to a deeper understanding of the health recov-ery process among coronavirus disease 2019(COVID-19)convalescents.Moreover,the findings help identify characteristic health risk factors associated with convalescents and highlight the risk of moderate/severe dis-orders and reinfection.Furthermore,the findings also provide valuable guidance and reference for SARS-CoV-2 rehabilitation strategies and the prevention of reinfection,offering insights for scientific recommendations.
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)DisordersReinfection
NHC Key Laboratory of Biosafety,National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases(NITFID),National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention(China CDC),Beijing 102206,China
College of Life Sciences,Beijing Normal University,Beijing 100875,China
Department of Epidemiology,School of Public Health,Cheeloo College of Medicine,Shandong University,Shandong 250100,China
School of Public Health and Management,Shandong First Medical University &Shandong Academy of Medical Sciences,Jinan 250117,China
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National Key Research and Development Program of ChinaNational Key Research and Development Program of ChinaNational Natural Science Foundation of China
NETL
NSTL
万方数据
