Effects of Immune Enhanced Enteral Nutrition on Nutritional Status,Lung Function and Humoral Immunity in Elderly Patients with Severe Pneumonia
Objective:To investigate the effects of immune enhanced enteral nutrition on nutritional status,lung function and hu-moral immunity in elderly patients with severe pneumonia(SP).Methods:104 elderly SP patients in our hospital from January 2021 to January 2023 were selected as research objects,and were randomly divided into control group and observation group with 52 cases in each group according to random drawing method.The control group received conventional enteral nutrition support,and the observation group received immune enhanced enteral nutrition support.The recovery time of symptoms and signs,severity of disease,pneumonia severity index,lung function,nutritional status,humoral immunity index before and after treatment were compared between the two groups.Results:The disappearance time of fever,cough,lung rales and X-ray shadow in observation group was shorter than that in con-trol group(P＜0.05).After treatment,the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)scores of the observation group were lower than those of the control group(P＜0.05);After treatment,the risk grade of pneumonia in observation group was better than that in control group(P＜0.05).After treatment,the levels of total protein(TP),prealbumin(PA),albumin(ALB)and transferrin(TRF)in observation group were higher than those in control group(P＜0.05);After treatment,the dynamic lung compliance(Cdyn)of ob-servation group was higher than that of control group,and airway resistance(R)was lower than that of control group(P＜0.05).After treatment,the levels of immunoglobulin A(IgA),immunoglobulin M(IgM),immunoglobulin G(IgG),complement C3 and complement C4 in observation group were higher than those in control group(P＜0.05).Conclusion:Immune enhanced enteral nutrition support can ac-celerate the relief of clinical symptoms and signs in elderly SP patients,improve their condition,pneumonia severity and lung function,and enhance their immune capacity and nutritional level,which has certain clinical application value.
NETL
NSTL
万方数据
