Predictive Value of Carotid Artery Ultrasound Quantitative Parameters Combined with MPV/PC Ratio and NLR for Poor Prognosis in Patients with Acute Ischemic Stroke
Objective:To investigate the predictive value of carotid artery ultrasound quantitative parameters combine with mean platelet volume(MPV)/platelet count(PC)ratio and neutrophil/lymphocyte ratio(NLR)for poor prognosis in patients with acute is-chemic stroke(AIS).Methods:97 AIS patients who were admitted to Hefei Second People's Hospital from March 2020 to March 2022 were selected,all patients underwent carotid artery ultrasound and blood routine examination,carotid artery ultrasound quantitative parameters were obtained,and MPV/PC ratio and NLR were calculated.The prognosis of patients 90 days after discharge was evaluated by modified Rankin scale(mRS),patients were divided into poor prognosis group and good prognosis group.The value of carotid artery ultrasound quantitative parameters,MPV/PC ratio and NLR in predicting poor prognosis of AIS patients were analyzed by receiver oper-ating characteristic(ROC)curve.Results:The intima-media thickness(IMT),end-diastolic blood flow velocity(EDV),MPV/PC ratio and NLR in poor prognosis group were higher than those in good prognosis group(P＜0.05),the peak systolic velocity(PSV)was lower than that in good prognosis group(P＜0.05).The areas under the curve of IMT,PSV,EDV,MPV/PC ratio and NLR in predicting poor prognosis of AIS patients were 0.751,0.710,0.693,0.769 and 0.771 respectively,the area under the curve of combined IMT,PSV,EDV,MPV/PC ratio and NLR in predicting poor prognosis of AIS patients was 0.883,higher than the individual index prediction.Conclusion:Carotid artery ultrasound quantitative parameters combined with MPV/PC ratio and NLR have high predictive value in the evaluation of poor prognosis of AIS patients.
Acute ischemic strokeCarotid artery ultrasoundPrognosisMPV/PC ratioNLRPredictive value
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