Efficacy of Xueshi No.4 Recipe Combined with Amlodipine Besylate Tablet in the Treatment of Hypertension of Damp Heat Invading Collaterals and Its Effect on Blood Lipids and Hemorheology
Objective:To observe the curative effect of Amlodipine besylate tablets combined with Xueshi No.4 recipe and its ef-fect on blood lipids and Hemorheology in patients with hypertension of dampness heat invading collaterals.Methods:120 patients with damp heat collateral invasion hypertension admitted to Shijiazhuang Traditional Chinese Medicine Hospital from January 2020 to De-cember 2022 were divided into the control group(n=60,treated with Amlodipine besylate tablets)and the combined group(n=60,treated with Xueshi No.4 recipe on the basis of the control group)by random number table.The clinical efficacy in two groups 4 weeks after treatment was observed,the blood pressure,traditional Chinese medicine syndrome scores,blood lipids and hemorheology before treat-ment and 4 weeks after treatment were compared between two groups.Results:The clinical total effective rate in combined group was higher than that in control group(P＜0.05).Systolic blood pressure(SBP)and diastolic blood pressure(DBP)in combined group at 4 weeks after treatment were lower than those in control group(P＜0.05).The traditional Chinese medicine syndrome scores of vertigo,headache,thirst and lack of drinking,limb fatigue,insomnia,palpitations,chest tightness,and limb numbness in combined group at 4 weeks after treatment were lower than those in control group(P＜0.05).The triglyceride(TG),total cholesterol(TC)and low-density lipoprotein cholesterol(LDL-C)in combined group at 4 weeks after treatment were lower than those in control group,while high-density lipoprotein cholesterol(HDL-C)in combined group at 4 weeks after treatment was higher than those in control group(P＜0.05).The ery-throcyte aggregation index,maximum platelet aggregation rate,whole blood high shear viscosity,and whole blood low shear viscosity in combined group at 4 weeks after treatment were lower than those in control group(P＜0.05).Conclusion:Xueshi No.4 recipe combined with amlodipine besylate tablet in the treatment of hypertension of damp heat invading collaterals,which can improve clinical efficacy,reduce blood pressure,reduce traditional Chinese medicine syndrome scores,and improve blood lipids and hemorheology.
NETL
NSTL
万方数据
