Effect of Tongdu Tiaoshen Acupuncture Combined with Cognitive Function Training on Intestinal Flora and Neurotransmitters in Patients with Post Stroke Cognitive Impairment
Objective:To observe the effect of Tongdu tiaoshen acupuncture combined with cognitive function training on neuro-transmitters and intestinal flora in patients with post stroke cognitive impairment.Methods:According to the random number table method,124 patients with post stroke cognitive impairment who were admitted to Cangzhou Integrated Traditional Chinese and Western Medicine Hospital of Hebei Province from July 2021 to October 2022 were divided into control group(62 cases,cognitive function train-ing)and observation group(62 cases,cognitive function training,Tongdu tiaoshen acupuncture combined treatment).Mini-mental state examination(MMSE),activities of daily living(ADL),Montreal cognitive assessment scale(MoCA),serum neurotransmitters[nore-pinephrine(NE),neurotransmitter acetylcholine(ACh),5-hydroxytryptamine(5-HT),dopamine(DA)]and intestinal flora indexes were compared between two groups.Results:30 days after treatment,the scores of MMSE,MoCA and ADL in observation group were higher than those in control group(P＜0.05).30 days after treatment,Ach,DA,NE and 5-HT in observation group were higher than those in con-trol group(P＜0.05).30 days after treatment,Escherichia coli and Enterococcus in observation group were lower than those in control group,and Bifidobacterium and Lactobacillus were higher than those in control group(P＜0.05).Conclusion:Patients with post stroke cognitive impairment combine with Tongdu tiaoshen acupuncture method on the basis of cognitive function training,which can signifi-cantly improve cognitive function,intestinal flora and neurotransmitter levels,which is conducive to improving patients'activities of daily living.
Tongdu tiaoshen acupuncture methodCognitive function trainingPost stroke cognitive impairmentIntestinal floraNeurotransmitters
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