Clinical Effect of Clearing Heat,Resolving Phlegm,Dispersing Lung and Spasmolysis on Bronchial Asthma and Its Influence on Airway Rspiratory Parameters and Quality of Life
Objective:To explore the clinical effect of clearing heat,resolving phlegm,dispersing lung and spasmolysis on bronchial asthma and its influence on airway respiratory parameters and quality of life.Methods:60 patients with bronchial asthma admitted to our hospital from October 2019 to September 2021 were selected as the study subjects.All patients were divided into observation group and matched group by random number table method,with 30 patients in each group.The matched group was given inhaled budeseide formoterol powder.The observation group was treated with the method of clearing heat,resolving phlegm,dispersing lung and spasmolysis on the basis of the matched group.The clinical effects of the two groups were compared,the changes of TCM syndrome integral,airway respiratory parameters,inflammatory factors and quality of life before and Post-treatment for 1 month.Results:The total effective rate of the observation group was higher than matched group(P＜0.05);There was no difference in the scores of TCM syndromes between the two groups Pretherapy(P＞0.05).Post-treatment,the two groups were lower,and the scores of the observation group were lower than those of the matched group(P＜0.05);There was no difference between the two groups in the forced expiratory volume in the first second(FEV1),forced vital capacity(FVC),forced expiratory volume/forced vital capacity in the first second(FEV1/FVC)and the maximum expiratory flow(PEF)in the first second(FEV1/FVC)Pretherapy(P＞0.05)PEF increased,and the observation group was higher than the matched group(P＜0.05);There were no difference in the pre-treatment tumor necrosis factor-α(TNF-α),transforming growth factor-β1(TGF-β1),matrix metalloprotein-9(MMP-9),Vascular endothelial growth factor(VEGF),interferon-γ(IFN-γ),and interleukin-4(IL-4)(P＞0.05).Post-treatment,TNF-α,TGF-β1,MMP-9,VE GF,IFN-γ,and IL-4 levels decreased,and the observed group was lower than the matched group(P＜0.05);There was no difference in the scores of quality of life between the two groups Pretherapy(P＞0.05).The scores of quality of life in the two groups were decreased 1 month Post-treatment,and the scores in the observation group were lower than those in the matched group(P＜0.05).Conclusion:Patients with bronchial asthma on the basis of conventional western medicine treatment by increasing phlegm and pulmonary spasmodiysis can reduce the symptoms.In addition,it can improve the respiratory function of patients,reduce the inflammatory factor response,and improve the quality of life of patients.
Bronchial asthmaClearing heat,resolving phlegm,dispersing lung and spasmolysisAirway respiratory parametersQuality of life
NETL
NSTL
万方数据
维普
