Effect of San'ao Tablets Combined with Budesonide Suspension Atomization Inhalation on Inflammatory Cytokines and T Lymphocyte Subsets in Children with Acute Bronchitis
Objective:To observe the effect of atomized inhalation of Budesonide suspension and combined treatment of San'ao tablet on T lymphocyte subsets and inflammatory cytokines in children with Acute bronchitis.Methods:78 children with acute bronchitis who were admitted to the Hefei Second People's Hospital from January 2021 to January 2023 were selected,and the children were divided into control group and study group according to the dichroism method,39 cases each.The children in control group received Budesonide suspension atomization inhalation,and the children in study group received San'ao tablets combined with Budesonide suspension atomization inhalation.The efficacy,inflammatory factor levels,clinical indicators,T lymphocyte subsets and medication safety between the two groups were compared between two groups.Results:The clinical total effective rate in study group was higher than that in control group(P＜0.05).The study group had shorter relief times for wheezing,coughing,normal body temperature,and lung rales compared to the control group(P＜0.05).7 d after treatment,the procalcitonin(PCT),interleukin-8(IL-8)and interleukin-6(IL-6)decreased in two groups,and study group were lower than those in control group(P＜0.05).7 d after treatment,the CD8+decreased in two groups,and study group was lower than that in control group(P＜0.05).The CD4+and CD4+/CD8+increased in two groups,and study group were higher than those in control group(P＜0.05).There was no statistically signifiicant difference in adverse reactions in children between two groups(P＞0.05).Conclusion:The treatment of children with Acute bronchitis by atomization inhalation of Budesonide suspension combined with San'ao tablet is helpful to shorten the time of clinical symptom relief,reduce the level of inflammatory cytokines and regulate T lymphocyte subsets.
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NSTL
万方数据
维普
