Effect of Renshen Yangrong Decoction Combined with Acupoint Application on Blood Lipid,Cardiac Function and Th1/Th2 Cytokines in Patients with Coronary Heart Disease after PCI
Objective:To observe the effect of renshen yangrong decoction combine with acupoint application on blood lipid,car-diac function and Th1/Th2 cytokines in patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods:142 postoperative patients with coronary heart disease undergoing PCI who were admitted to our hospital from February 2020 to Decem-ber 2022 were selected.The patients were divided by the double chromosphere method into a control group and an experimental group using the dual color sphere method,with 71 cases in each group.The control group received routine Western medicine treatment and acupoint application,while the experimental group received ginseng nourishing rong decoction on the basis of the control group,all treat-ed for 4 weeks.Observe and compare two groups of traditional Chinese medicine syndrome scores,cardiac function indicators[left ven-tricular ejection fraction(LVEF)and cardiac output per minute(CO)],four indicators of blood lipids[triacylglycerol(TG),total choles-terol(TC),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C)],Th1/Th2 type cytokines[sub γInterferon(IFN-γ),Interleukin(IL)-2,IL-4,IL-10.The incidence of cardiovascular adverse events within half a year after the end of treatment in both groups was also recorded.Results:After treatment,the main symptom score,secondary symptom score,and total score of the two groups decreased,and the experimental group was lower than the control group,which showed statistical difference(P＜0.05).After treatment,left ventricular ejection fraction(LVEF)and cardiac output per minute(CO)increased in both groups,and the experi-mental group was higher than the control group,which showed statistical difference(P＜0.05).After treatment,HDL-C increased in both groups,and the experimental group was higher than the control group;TG,TC,and LDL-C decreased,and the experimental group was lower than the control group,the difference was statistically significant(P＜0.05).After treatment,IL-4 and IL-10 levels increased in both groups,and the experimental group was higher than the control group;IFN-γ,IL-2 decreased and the experimental group was lower than the control group,which showed statistical difference(P＜0.05).There was no statistically significant difference in the incidence of cardio-vascular adverse events in two groups(P＞0.05).Conclusion:Renshen yangrong decoction combine with acupoint application for patients with coronary heart disease after PCI,which can improve the blood lipid and cardiac function of patients,regulate Th1/Th2 cy-tokines,and promote clinical outcomes.
万方数据
维普
