Comparison of the Effects of Continuous Hemodialysis at Room Temperature and Mild Hypothermia on Postoperative Cardiogenic Shock in Patients with Valve Disease and Its Impact on Cardiac Function,Heart Failure Indicators,and Inflammatory Factors
Objective:To compare the effects of continuous hemodialysis at room temperature and mild hypothermia on postoper-ative cardiogenic shock in patients with valve disease,as well as its impact on cardiac function,heart failure indicators,and inflammatory factors.Methods:90 patients of postoperative cardiogenic shock after valvular disease admitted from January 2020 to December 2022 were selected and divided into observation group and control group with 45 cases each.The control group patients were treated with con-tinuous hemodialysis at room temperature,while the observation group patients were treated with continuous hemodialysis treatment at mild hypothermia.The postoperative drainage volume,blood purification time,ventilator assistance time,ICU stay time,as well as the incidence of death,arrhythmia,and infection were compared between the two groups of patients.The left ventricular ejection fraction(LVEF)before and after treatment was compared between the two groups of patients Left ventricular end systolic volume(LVESV),left ventricular end diastolic volume(LVEDV),cardiac function indicators,BNP(B-type natriuretic peptide,B-type natriuretic peptide),hy-persensitive C-reactive protein(hs CRP),and blood creatinine(Cr)laboratory indicators for heart failure,Interleukin-6(IL-6),Inter-leukin-1(IL-1),Tumor Necrosis Factor-α(TNF-α)Inflammatory factor expression level.Results:There was no difference in the incidence of arrhythmia and infection between the two groups(P＞0.05),postoperative drainage rate,ventilator assisted time ICU admission time,blood purification time and mortality in the observation group were lower than that of the control group(P＜0.05);There was no signifi-cant difference in LVESV,LVEF and LVEDV between the two groups before treatment(P＞0.05),LVEF was elevated in both groups after treatment,and the observation group was higher than the control group,Lower levels of LVESV and LVEDV,The observation group was lower than the control group(P＜0.05);BNP,hs-CRP,and Cr between the two groups before treatment(P＞0.05),After treat-ment,BNP,hs-CRP,and Cr related HF laboratory indicators were decreased in both groups.The observation group was lower than the control group(P＜0.05);The levels of interleukin-6(IL-6),Ileukin-1(IL-1),tumor necrosis factor-α(TNF-α)were not different between the two groups(P＞0.05),both levels were reduced after the treatment,and the observation group was lower than the control group(P＜0.05).Conclusion:Compared with normothermic hemodialysis,mild hypothermia blood purification treatment can further reduce postoperative drainage flow and blood purification time,promote early recovery,and reduce patient mortality.At the same time,adopting mild hy-pothermia hemodialysis treatment can further improve patient heart function,alleviate heart failure,and lower the level of inflammatory factors in the patient's body.
Normal temperatureMild low temperatureHemodialysisValve diseaseCardiogenic shockCardiac functionInflam-matory factors
万方数据
维普
