Efficacy of Wrist-Ankle Acupuncture Combined with Auricular Point Pressing Beans in the Treatment of Liver Cancer Pain and its Effect on Psychological Status and Serum Pain Mediator
Objective:To observe the efficacy of wrist-ankle acupuncture combine with auricular point pressing beans in the treat-ment of cancer pain of primary liver cancer(PHC)and its effect on psychological status and serum pain mediator.Methods:117 PHC cancer pain patients admitted to the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine from March 2020 to December 2022 were selected,patients were divided into control group and combined group according to the random number table method,with 58 cases and 59 cases respectively.Both groups received routine pain treatment,control group received auricular point pressing beans,and combined group received wrist-ankle acupuncture on the basis of control group.The pain relief rate,clinical indica-tors,psychological status and pain mediator levels were compared between two groups.Results:The pain relief rate in combined group was higher than that in control group(P<0.05).The digital pain method(NRS)score in combined group was lower than that in control group,the pain onset time and duration of each pain were shorter than those in control group,and the outbreak pain times were less than those in control group(P<0.05).After treatment,the scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)in two groups decreased,and combined group was lower than that of control group(P<0.05).After treatment,5-hydroxytryptamine(5-HT),sub-stance P(SP)and prostaglandin E2(PGE2)in two groups decreased,and combined group were lower than that of control group(P<0.05).Conclusion:Wrist-ankle acupuncture combined with auricular point pressing beans in the treatment of PHC cancer pain,which could ef-fectively relieve pain symptoms,reduce the level of serum pain mediator,and effectively regulate the psychological status of patients,with good application value.
Wrist-ankle acupunctureAuricular point pressing beansLiver cancer painEfficacyPsychological statusPain mediator