Analysis on The Curative Effect and Prognostic Factors of Xuanfei Jieasmolasqingrefang in the Treatment of Young Patients with Heat Asthma
Objective:To explore the efficacy and prognostic factors of Xuanfei Jiaoji Qingre decoction in the treatment of young patients with hot wheezing.Methods:Sixty young patients with febrile croup admitted to our hospital from October 2019 to September 2021 were selected as the subjects of this study,and they were divided into 2 groups according to different treatment methods,observa-tion group,n=30,and control group,n=30.The control group was treated with budesonide formoterol powder inhalation based on their severity on the basis of conventional treatment such as oxygenation and sputum dissolution.In the observation group,based on the con-trol group,the adjuvant treatment of Xuanfei antispasmodic and clearing heat formula was added.The relevant factors,adult asthma sur-vival quality rating scale(AQLQ)and treatment effect were compared before and after treatment between the groups,and the patients were divided into good prognosis group(n=40)and poor prognosis group(n=20)according to their prognosis effect,and the prognosis of patients with febrile croup was analyzed unilaterally and logistic regression analysis was conducted to determine the independent factors affecting prognosis.Results:Before treatment,there was no difference in the comparison of interleukin-4(IL-4),interferon-γ(IFN-γ),FEV,st second expiratory volume/exertional spirometry(FEV1/FVC)levels and AQLQ scores between the observation and control groups(P＞0.05),after treatment,compared with before treatment,IL-4 levels were lower in the observation group,and IFN-γ levels,FEV1/FVC levels and AQLQ scores were higher in the observation group,and the levels were higher in the observation group(P＜0.05);Treatment group effective rate in the observation group was higher than control group(P＜0.05);In the analysis of influencing factors for the prognosis of hot wheezing in adolescents,the results showed that the course of disease,BMI,allergic rhinitis,genetic factors,age of onset,number of respiratory tract infections,smoking history,and frequency of attacks were all single factors affecting the prognosis of hot wheezing(P＜0.05).Compliance,skin eczema and route of administration did not have a great influence on the prognosis of hot wheeze(P＞0.05).The single factors affecting the prognosis of heat asthma were assigned values and included in the Logistic regression analysis.The course of disease,BMI,allergic rhinitis,genetic factors,age of onset,frequency of respiratory tract infection,smoking his-tory and frequency of attack were used as independent variables.Course,BMI,allergic rhinitis,genetic factors,smoking history,seizure frequency is the independent factors influencing the prognosis of hot xiao(P＜0.05).Conclusions:Xuanfei spasmolysis heat can effectively regulate young fever patients body inflammation factor and lung function,improve the quality of life and treatment effect,according to the prognosis of effect in patients with fever,course,BMI,allergic rhinitis,genetic factors,smoking history,attack frequency is an inde-pendent factor affecting the prognosis of fever,can be targeted intervention,to improve the prognosis effect in patients.
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维普
