Effects of Cognitive Behavioral Therapy on Stress Response,Psychological Resilience and Immune Function in Patients Undergoing Laparoscopic Radical Nephrectomy
Objective:To explore the effect of cognitive behavioral therapy on stress response,psychological elasticity and immune function in patients undergoing laparoscopic radical nephrectomy,and to provide reference for improving the rehabilitation effect of patients undergoing laparoscopic radical nephrectomy.Methods:According to the coin toss method,80 patients with laparoscopic radical nephrectomy admitted to Nanjing Drum Tower Hospital from January 2019 to December 2022 were randomly divided into control group and observation group.40 patients in the control group received routine intervention,and 40 patients in the observation group received cognitive behavioral therapy intervention.The changes of clinical basic indexes,stress response,psychological elasticity,immune function and quality of life were compared between the two groups.Results:After intervention,the exhaust time,catheter indwelling time,off-bed activity time and hospitalization time in the observation group were shorter than those in the control group(P＜0.05).After intervention,the levels of cortisol and epinephrine and the scores of psychological resilience in the two groups were higher than those before intervention(P＜0.05),and the levels of cortisol and epinephrine in the observation group were lower than those in the control group,and the scores of psychological resilience were higher than those in the control group(P＜0.05).After intervention,the levels of CD3+,CD4+and CD4+/CD8+in the two groups were higher than those before intervention,and the level of CD8+was lower than that before intervention(P＜0.05).The levels of CD3+,CD4+and CD4+/CD8+in the observation group were higher than those in the control group,and the level of CD8+was lower than that in the control group(P＜0.05).The scores of quality of life in the two groups after intervention were higher than those before intervention(P＜0.05),and those in the observation group were higher than the control group(P＜0.05).Conclusion:The intervention of cognitive behavioral therapy in patients undergoing laparoscopic radical nephrectomy can not only effectively improve the negative emotions of patients,improve their mental elasticity,but also reduce the stress response of patients,improve the immune function of the body,and accelerate the postoperative rehabilitation process,which is worthy of clinical reference and application.
Cognitive behavioral therapyLaparoscopic radical nephrectomyStress reactionPsychological resilienceImmune function
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