Effects of Xiaonang Tiaojing Decoction Combined with Diane-35 on Sex Hormones,Lipid Metabolism and Ovarian Stromal Blood Flow in Patients with Polycystic Ovary Syndrome
Objective:To observe the effects of xiaonang tiaojing decoction combined with diane-35 on sex hormones,lipid metabolism and ovarian stromal blood flow in patients with polycystic ovary syndrome(PCOS).Methods:117 patients with PCOS who were admitted to Henan Provincial Hospital of Traditional Chinese Medicine from July 2020 to December 2022 were selected.Patients were divided into control group(diane-35,58 cases)and study group(xiaonang tiaojing decoction combined with diane-35,59 cases)according to the random number table method.The sex hormone indexes[luteinizing hormone(LH),estradiol(E2),follicle stimulating hormone(FSH),testosterone(T)],chinese medicine syndrome scores,lipid metabolism[high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),triglyceride(TG),total cholesterol(TC)]and ovarian stromal blood flow[uterine artery pulsation index(PI),uterine artery resistance index(RI)]were compared between two groups.Results:The main symptom score,secondary symptom score and total score in study group were lower than those in control group after treatment(P＜0.05).LH,E2,FSH and T in study group were lower than those in control group after treatment(P＜0.05).HDL-C in study group was higher than that in control group;TC,TG and LDL-C were lower than those in control group after treatment(P＜0.05).PI and RI in study group were lower than those in control group after treatment(P＜0.05).Conclusion:Xiaonang tiaojing decoction combined with diane-35 in the treatment of PCOS patients,which can improve the clinical symptoms of patients,regulate the body's sex hormones,lipid metabolism and ovarian stromal blood flow,and the curative effect is good.
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