Analysis of Risk Factors for Clinical Characteristics and Disease Severity in Patients with Hyperlipidemia Combined with Hypertension
Objective:To analyze the risk factors for clinical characteristics and disease severity in patients with hyperlipidemia combined with hypertension.Methods:A total of 532 patients with hypertension and hyperlipidemia admitted to our hospital from December 2021 to December 2022 were retrospectively analyzed and divided into the hyperlipidemia group(n=240)and the hyperlipidemia combined with hypertension group(n=292)based on their blood pressure and lipid levels.The independent risk factors affecting the severity of disease in patients with hyperlipidemia combined with hypertension were analyzed by binary classification logistic regression.Results:Smoking history of hyperlipidemia with hypertension,family history,history of diabetes,hyperlipidemia history and serum triglycerides(TG),total cholesterol(TC),low density lipoprotein(LDL),high-density lipoprotein(HDL),blood uric acid(UA),C reactive protein(CRP)levels were different from the high lipid group(P＜0.05).In the severe hyperlipidemia combined with hypertension group,the levels of smoking history,family history,having diabetes,hypertension and serum UA and CRP were higher than those in the moderate group(P＜0.05).Binary classification logistic regression analysis showed that a history of smoking,family history,having diabetes,hypertension and elevated serum UA and CRP levels were independent risk factors for the severity of the disease in patients with hyperlipidemia combined with hypertension(P＜0.05).Conclusion:History of smoking,family history,diabetes mellitus,hypertension,elevated UA levels and CRP levels are independent risk factors for the severity of hyperlipidemia combined with hypertension and can be used as clinical indicators for the progression of hyperlipidemia combined with hypertension.
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