Effects of Naomaili Granules Combined with Edaravone Dextrorphan Injection Concentrate Solution on Neurological Function,Hemorheology and Oxidative Stress in Patients with Acute Cerebral Infarction
Objective:To investigate the effects of naomaili granules combined with edaravone dextrorphan injection concentrate solution on neurological function,hemorheology and oxidative stress in patients with acute cerebral infarction(ACI).Methods:140 ACI patients admitted to Nanjing Central Hospital and Changzhou First People's Hospital from July 2022 to July 2023 were selected,and pa-tients were divided into control group(n=70,conventional treatment combined with edaravone dextrorphan injection concentrate solution treatment)and observation group(n=70,received naomaili granules treatment on the basis of control group)according to random number table method.The efficacy,neurological function,activities of daily living,hemorheology and oxidative stress were compared in two groups.Results:The total clinical effective rate in observation group was higher than that in control group(P＜0.05).The National Insti-tutes of Health Stroke Scale(NIHSS),plasma viscosity,whole blood low shear viscosity,whole blood high shear viscosity,packet cell volume and malondialdehyde(MDA)in observation group were lower than those in control group after treatment,and daily living ability scale score(Barthel index)score and superoxide dismutase(SOD)in observation group were higher than those in control group(P＜0.05).Conclusion:The combination of naomaili granules and edaravone dextroborneol injection concentrate solution in the treatment of ACI patients,which is helpful to regulate hemorheology,improve neurological function,reduce oxidative stress and improve their activities of daily living.
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