Effect of Danggui Mingmu Decoction Combined with Intravitreal Injection of Aflibercept on Intraocular Pressure and Retinal Thickness in Patients with Age-related Macular Degeneration
Objective:To analyze the effect of Danggui Mingmu Decoction combined with intravitreal injection of aflibercept on intraocular pressure and retinal thickness in patients with age-related macular degeneration(AMD).Methods:The clinical data of 80 AMD patients admitted to our hospital from February 2022 to February 2023 were retrospectively analyzed,and they were divided into control group and observation group according to the treatment methods.In each group,40 cases,the control group were given intrabul-bar injection abercept,and the observation group was treated with Angelica Mingmu Decoction on the basis of the control group.IOP,macular foveal retinal thickness(CRT),parfoveal thickness(PMT),macular foveal blood flow density,parfoveal blood flow density,best corrected visual acuity(BCVA),and choroidal neo vascular(CNV)area levels before and 1 week,1 month,and 3 months after treatment.Results:After 1 week,1 month and 3 months of treatment,the intraocular pressure of the two groups was lower than that before treat-ment,and the intraocular pressure of the observation group was lower than that of the control group(P＜0.05).After treatment,compared with the control group,the CRT,macular foveal thickness and macular foveal blood flow density in the observation group were lower(P＜0.05).After 1 week,1 month and 3 months of treatment,the BCVA levels of the two groups were lower than those before treatment,and the BCVA level of the observation group was lower than that of the control group(P＜0.05).Compared with before treatment,the CNV area of the two groups was lower after 1 week,1 month and 3 months of treatment(P＜0.05).Conclusion:Danggui Mingmu Decoc-tion combined with intravitreal injection of aflibercept is beneficial to stabilize the intraocular pressure of AMD patients,reduce the vas-cular density and retinal thickness in macular area,and improve the visual acuity of patients to a certain extent.
Age-related macular degenerationDanggui Mingmu DecoctionIntraocular injection of afliberceptIntraocular pres-sureRetinal thickness
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