Effects of Electroacupuncture Stimulation Anesthesia at Acupoints on Anesthesia Effect,Stress Response and Immune Function in Elderly Patients Undergoing Radical Resection of Rectal Cancer
Objective:To observe the effects of electroacupuncture stimulation anesthesia at acupoints on anesthesia effect,stress response and immune function in elderly patients undergoing radical resection of rectal cancer.Methods:97 elderly patients who under-went radical resection of rectal cancer in our hospital from January 2022 to May 2023 were divided into control group(n=48,total intra-venous anesthesia)and observation group(n=49,on the basis of control group received electroacupuncture stimulation anesthesia at acu-points)by random number table method.The additional amount of anesthetic drugs,hemodynamics,pain score,Immune function indica-tors,stress response indicators and adverse reactions were compared between two groups.Results:Compared with control group,the dosage of vecuronium bromide,propofol and remifentanil in observation group were less(P＜0.05).Compared with control group,the mean arterial pressure and respiratory rate in observation group were lower at the time points from anesthesia induction period(Tl)to the end of anesthesia(T3)(P＜0.05).Compared with control group,the pain visual analogue score(VAS)in observation group was lower at 6 h,12 h and 24 h after operation(P＜0.05).Compared with control group,CD8+in observation group was lower,CD4+,natural killer(NK)cells,CD4+/CD8+were higher,and norepinephrine,adrenal gland and cortisol were lower(P＜0.05).There was no difference in the incidence of adverse reactions between two groups(P＞0.05).Conclusion:Electroacupuncture stimulation anesthesia at acupoints for el-derly patients undergoing radical resection of rectal cancer,which can reduce the dosage of other anesthetics,relieve pain,maintain hemodynamic stability,reduce stress response,improve immunosuppression,and have good anesthetic effect.
Electroacupuncture stimulation anesthesia at acupointsElderlyRadical resection of rectal cancerAnesthesia effectStress responseImmune function
NETL
NSTL
万方数据
