The Effect of Ruxanjie Granule Combined with Danazole on Endocrine Hormone and Body Mass Index in Elderly Women with Mammary Hyperplasia
Objective:This study was to investigate the efficacy of Ruxanjie Granule combined with Danazole in the treatment of endocrine hormones and body mass index in elderly women with mammary hyperplasia.Methods:A total of 102 elderly women with mammary hyperplasia diagnosed and treated in our hospital from April 2020 to April 2023 were selected,and were divided into the con-trol group(treated with danazole)and the study group(treated with Ruxanjie granule combined with danazole)with 51 cases in each group.The clinical efficacy and adverse reactions after treatment were compared between the two groups.Endocrine hormones,body mass index,immune function,pain degree and quality of life were measured before and after treatment.Results:(1)After treatment,the clinical efficacy of the study group was higher than that of the control group(P<0.05);(2)After treatment,the levels of T,P,E2 and PRL in the study group were higher than those in the control group(P<0.05).(3)After treatment,the levels of CD4+,IgG and IgA in the study group were higher than those in the control group(P<0.05).(4)After treatment,the pain degree of the study group was lower than that of the control group(P<0.05);(5)After treatment,the scores in the study group were higher than those in the control groupt(P<0.05);(6)After treatment,the adverse reactions in the study group were lower than those in the control group(P<0.05).Conclusion:Ruxanjie Gran-ule combined with Danazole can effectively treat the elderly women with mammary hyperplasia,regulate the level of endocrine hor-mones,and do not affect the body mass index,which is worthy of clinical application.
Ruxanjie GranuleDanazolMammary hyperplasiaOlder womenEndocrine hormoneBody mass indexCurative effect