Clinical Characteristics and Drug Resistance Analysis of Salmonella Infection in Children in Foshan Area From 2018 to 2022
Objective:To analyze the clinical characteristics and drug resistance of Salmonella infection in children in Foshan area from 2018 to 2022,and provide a basis for the clinical prevention and treatment of Salmonella infection.Methods:A retrospective analy-sis was conducted on 186 cases of pediatric Salmonella infection collected in Foshan Women and Children Hospital from January 1,2018 to December 31,2022.The general information of the patient,time distribution characteristics,clinical characteristics,serotype distribu-tion and drug resistance of pediatric Salmonella infection were analyzed.Results:The age distribution of 186 children with Salmonella infection was highest in the age group of 1-3 years old,accounting for 37.63％,and lowest in the age group of＞6 years old,accounting for 1.61％.33 cases occurred in 2018,19 cases in 2019,39 cases in 2020,44 cases in 2021,and 51 cases in 2022.The overall number of Salmonella infection cases is showing an upward trend;There are salmonella infection cases all year round,and the highest incidence rate is in summer and autumn,accounting for 43.55％and 30.11％respectively.Fever,diarrhea,and defecation are the main symptoms,ac-counting for 90.32％,74.73％and 63.98％,respectively.The highest serotype B group was 118 cases,accounting for 63.44％.Through the analysis of the drug sensitivity test of 191 isolated Salmonella strains,only 3 strains(1.57％)were found to be non resistant to the detected antibiotics,while 157 strains(82.20％)were resistant to class 3 or more multidrug-resistant salmonella.The resistance rates of gentamicin,cefazolin,and cefotetan were all 100％.There was a statistically significant difference in the resistance rate of levofloxacin,ciprofloxacin and achromycin among different years(P＜0 05).Conclusion:In recent years,the incidence of Salmonella infection in children in Foshan area has been on the rise.Children aged 1-3 are the main group,and summer and autumn are the peak seasons of the disease.The main serotype is Group B.Children infected with Salmonella are mainly characterized by fever,diarrhea,and defecation.The drug resistance of Salmonella is relatively severe,and relevant departments should pay attention to it.
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