Pathogen Bacteria Distribution and Logistic Regression Analysis of Influencing Factors in Postoperative Blood Flow Infections in Patients with Stanford Type A Aortic Dissection
Objective:To analyze the pathogen bacteria distribution and influencing factors of postoperative blood flow infection pathogens in patients with Stanford type A aortic dissection.Methods:102 patients with Stanford type A aortic dissection admitted to The First Affiliated Hospital of Xinjiang Medical University from June 2020 to January 2023 were selected as the study subjects.All patients received surgical treatment,and the incidence of postoperative bloodstream infections and pathogen bacteria distribution were analyzed.Patients were divided into infected group(n=17)and uninfected group(n=85)based on the incidence of postoperative bloodstream infec-tions.Collected clinical data from patients,and univariate and multivariate logistic regression to were used to analyze the risk factors for postoperative bloodstream infection in Stanford type A aortic dissection patients.Results:102 patients with Stanford type A aortic dissec-tion,17 experienced postoperative bloodstream infections,with an infection rate of 16.67％.45 strains of pathogens were isolated from 17 patients with bloodstream infections,including 29 strains of Gram negative bacteria(64.44％),13 strains of Gram positive bacteria(28.89％),and 3 strains of fungi(6.67％).The age,diabetes history,antibiotic treatment course,surgical duration,proportion of implanta-tion of artificial valves,proportion of secondary tracheal intubation,proportion of mechanical ventilation,and duration of deep vein catheterization in the infected group were all higher than those in the uninfected group(P＜0.05).Multivariate logistic regression analysis found that advanced age,second endotracheal intubation,mechanical ventilation,long time of deep vein catheterization,long surgical du-ration,and high proportion of implantation of artificial valves were independent risk factors for postoperative blood flow infection.Con-clusion:The patients with Stanford A aortic dissection have a high incidence of blood flow infection after surgery,and the main pathogens of infection are Gram negative bacteria.The risk factors of blood flow infection after surgery are the advanced age,secondary tracheal intubation,mechanical ventilation,long time of deep vein catheterization,long surgical duration,and high proportion of implan-tation of artificial valves.
Stanford type A aortic dissectionBlood flow infectionPathogenic bacteriaInfluencing factorsLogistic regression analysis
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