Effect of Qingre Cuyu Decoction Sitz Bath on Wound Healing after Mixed Hemorrhoids Operation and its Impact on Anorectal Dynamics and Neovascularization
Objective:To observe the effect of qingre cuyu decoction sitz bath on wound healing after mixed hemorrhoids opera-tion and its impact on anorectal dynamics and neovascularization.Methods:116 mixed hemorrhoids patients admitted to the First Affili-ated Hospital of Hunan University of Traditional Chinese Medicine from January 2021 to June 2022 were divided into control group(routine treatment,n=58)and experimental group(received qingre cuyu decoction sitz bath treatment on the basis of routine treatment,n=58)according to the random number table method.The efficacy,wound improvement situation,anorectal dynamics and neovascular-ization indexes were compared between two groups.Results:The total clinical effective rate in experimental group was higher than that in control group(P＜0.05).The edema disappearance time,wound pain disappearance time,wound healing time and granulation tissue growth time in experimental group were shorter than those in control group(P＜0.05).6 weeks after treatment,the maximum systolic pres-sure(MSP),high pressure zone length(HPZ)and maximum tolerable volume(MTV)of rectum in two groups decreased,and experimen-tal group was lower than that of control group(P＜0.05);the rectal resting pressure(RRP)increased,and experimental group was higher than that of control group(P＜0.05).6 weeks after treatment,the levels of vascular endothelial growth factor(VEGF),basic fibroblast growth factor(bFGF)and platelet-derived growth factor(PDGF)in two groups increased,and experimental group was higher than that of control group(P＜0.05).Conclusion:Qingre cuyu decoction sitz bath could promote wound healing after mixed hemorrhoids operation,promote neovascularization,and improve anorectal dynamics.
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