Effects of Yanlu Rukang Capsules Combined with Tamoxifen Citrate Tablets on Breast Ultrasound Indexes,Sex Hormone Indexes and Vascular Hyperplasia Indexes in Patients with Breast Hyperplasia
Objective:To observe the effects of yanlu rukang capsules combined with tamoxifen citrate tablets on breast ultrasound indexes,sex hormone indexes and vascular hypcrplasia indexes in patients with breast hyperplasia.Methods:130 patients with breast hyperplasia admitted to Hunan Provincial Maternal and Child Health Hospital were selected,and patients were divided into control group(n=65,tamoxifen citrate tablets treatment)and study group(n=65,yanlu rukang capsules treatment on the basis of control group)according to the random number table method.The efficacy,sex hormone indexes,vascular hyperplasia indexes and breast ultrasound indexes in two groups were compared,and the adverse reactions in two groups during treatment were observed.Results:The total clinical effective rate of the study group was 95.38％,which was higher than 78.46％in the control group(P＜0.05).Estradiol,vascular endothelial growth factor(VEGF),prolactin and basic fibroblast growth factor(bFGF)in study group were lower than those in control group after treatment,and progesterone was higher than that in control group(P＜0.05).The diameter of the low echo area,the inner diameter of the widest breast duct,the thickness of the thickest breast gland layer and the diameter of the cyst in study group were smaller than those in control group after treatment(P＜0.05).There was no difference in the incidence of adverse reactions between two groups(P＞0.05).Conclusion:The combination of yanlu rukang capsules on the basis of tamoxifen citrate tablets in patients with breast hyperplasia,which can improve breast ultrasound indexes and improve clinical efficacy,it may be relate to the improvement of sex hormone indexes and vascular hyperplasia.
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