Prognostic Value of Quantitative Parameters of Transcranial Doppler Hemodynamics in Young Patients with Stroke
Objective:Analyzing the value of quantitative transcranial doppler hemodynamic parameters in predicting prognosis in young stroke patients.Methods:Cases were included from April 2018 to December 2022,originating from the First Hospital of Qinhuangdao City,and the study population consisted of 349 young stroke patients,which were treated as a case group,according to disease,they were divided into mild,moderate and severe groups,with the numbers of cases being 97,196,and 56,and according to the prognosis,they were divided into poor prognosis and good prognosis groups,with the numbers of cases being 27 and 322.358 healthy young people as the control.The hemodynamic quantitative parameters were compared between the case and control group,patients with different severity of disease and different prognosis.The correlation and predictive value between hemodynamic quantitative parameters and the severity of disease and prognosis of patients were analyzed.Results:Compared to the control,PI of middle cerebral artery in case group was higher,Vm,Vs,Vd,BHI and rCBFLI were lower(P＜0.05).PI in the severe was higher than moderate and mild group(P＜0.05),moderate was higher than mild group(P＜0.05).Vm,Vs,Vd,BHI,rCBFLI of the severe were lower than moderate and mild group(P＜0.05),moderate were lower than mild group(P＜0.05).PI of MCA in the poor prognosis was higher than good prognosis group(P＜0.05),BHI and rCBFLI of MCA in the poor prognosis were lower than good prognosis group(P＜0.05).PI was positively correlated with the severity and prognosis of patients(P＜0.05).Vm,Vs,Vd,BHI,rCBFLI of MCA were negatively correlated with the severity of patients(P＜0.05).BHI and rCBFLI of middle cerebral artery were negatively correlated with the prognosis of patients(P＜0.05).The AUC value of combined detection of PI,BHI and rCBFLI in predicting the prognosis of young stroke patients was 0.864,higher than PI,BHI and rCBFLI alone(0.698,0.737,0.782,P＜0.05).The sensitivity of middle cerebral artery BHI and combined detection were 85.19％and 81.48％respectively,which were higher than that of middle cerebral artery PI and rCBFLI alone(66.67％and 62.96％,P＜0.05).The specificity of rCBFLI and combined detection of MCA was 81.68％and 78.26％respectively,which was higher than that of PI and BHI alone(64.29％and 67.08％,P＜0.05).Conclusion:PI was higher and Vm,Vs,Vd,BHI,rCBFLI were lower in young patients with stroke,and PI increased with the aggravation of the patient's condition,while Vm,Vs,Vd,BHI,rCBFLI decreased with the aggravation of the patient's condition.PI,BHI,rCBFLI could be used to evaluate the prognosis of the patients,and the combined detection of the three had higher predictive value.
StrokeYouthTranscranial dopplerHemodynamicsPrognosisPredictive value
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