Effects of Huoxin Pill Combined with Nicorandil on Cardiac Function,Blood Lipid and Hemorheology in Patients with Stable Angina Pectoris of Coronary Heart Disease
Objective:To observe the effects of huoxin pills combined with nicorandil on cardiac function,blood lipid and hemorheology in patients with stable angina pectoris(SA)of coronary heart disease.Methods:According to the random number table method,130 SA patients with coronary heart disease admitted to our hospital from August 2020 to February 2022 were divided into con-trol group(nicorandil treatment,n=65)and combined group(nicorandil combine with huoxin pill treatment,n=65).The cardiac function indexes,clinical symptom improvement,hemorheology indexes,blood lipid indexes,efficacy and adverse reactions were compared be-tween two groups.Results:The total effective rate in control group was lower than that in combined group(P＜0.05).Compared with con-trol group 3 months after treatment,the duration of angina pectoris in combined group was shorter,the number of episodes per week was less,the stroke volume(CO),high-density lipoprotein cholesterol(HDL-C),left ventricular ejection fraction(LVEF)were higher,total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),left ventricular end-diastolic diameter(LVEDD),triglyceride(TG),whole blood viscosity high shear/low shear,plasma viscosity,fibrinogen were lower(P＜0.05).There was no difference in the incidence of ad-verse reactions between the control group and the combined group(P＞0.05).Conclusion:The treatment of coronary heart disease SA with huoxin pills combined with nicorandil,which can improve clinical efficacy,improve cardiac function,and regulate blood lipid and hemorheology.
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