Clinical Effect of Conbercept in the Treatment of Different OCT Types of Retinal Vein Occlusion Induced Macular Edema and the Influence on Vision and CRT
Objective:To observe the clinical efficacy of conbercept in the treatment of different optical coherence tomography(OCT)types of retinal vein occlusion(RVO)induced macular edema(ME),and the influence on vision and central retinal thickness(CRT).Methods:A total of 60 patients with RVO induced ME who were admitted to the hospital from January 2020 to June 2023 were selected,and divided into the diffuse retinal thickening(DRT)group(n=24),the cystoid macular edema(CME)group(n=21)and the serous retinal detachment(SRD)group(n=15)according to OCT classification.All patients were treated with conbercept.Clinical efficacy 6 months after treatment,visual acuity and CRT before and after treatment were compared among the 3 groups.The incidence rates of complications within 6 months of treatment were calculated.Results:The total clinical response rate in the DRT group(91.67％)was sig-nificantly higher than that in the CME group(61.90％)and the SRD group(66.67％)(P＜0.05).3 months and 6 months after treatment,log-MAR BCVA and CRT in the 3 groups were lower than those before treatment(P＜0.05).The logMAR BCVA and CRT in the DRT group were lower than those in the CME group and the SRD group(P＜0.05),but there was no statistically significant difference between the CME group and the SRD group(P＞0.05).There was no statistically significant difference in the total incidence of complications among the 3 groups 6 months after treatment(P＞0.05).Conclusion:Conbercept is effective in the treatment of patients with RVO induced ME.It is conducive to improving vision and CRT,with high safety.The therapeutic effect on DRT is better than other OCT types.
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