Effects of Enteral Nutrition on Inflammatory Stress and the Influencing Factors of Intestinal Flora Disorder in Patients with Severe Stroke
Objective:To analyze the effects of enteral nutrition on inflammatory stress and the influencing factors of intestinal flora disorder in patients with severe stroke.Methods:82 severe stroke patients admitted from January 2022 to May 2023 were divided into control group and observation group,41 each.The control group was treated with conventional treatment,and the observation group was treated with enteral nutrition.Compison of inflammatory response index,stress response index,APACHE Ⅱ score,and GCS score before and after treatment,and analyze factors influencing the occurrence of intestinal dysbiosis.Results:Post-treatment,compared with the matched group:C-reactive protein(hs-CRP),interleukin-2(IL-2),IL-6,tumor necrosis factor-α(TNF-α),noradrenaline(NE),cortisol(COR)and APACHE Ⅱ score,alpha-1,glutathione,GSH-1)(GSH-Px),GCS score(P＜0.05);by factor analysis,endotoxin,hypertension and diabetes were independent risk factors for intestinal dysfunction in severe stroke patients(P＜0.05).Conclusion:Enteral nutrition ther-apy can effectively reduce the degree of inflammatory stress in patients with severe stroke,and then increase the clinical benefit of patients,and the occurrence of intestinal flora imbalance in patients is related to hypertension,diabetes and high levels of endotoxin.
Severe strokeEnteral nutritionInflammationStressIntestinal flora disorderInfluencing factor
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