A Retrospective Study on the Effect of Bailing Capsule on Microinflammation and Renal Function in Patients with Diabetic Nephropathy
Objective:To retrospectively analyze the effect of Bailing capsule on microinflammation and renal function in patients with diabetic nephropathy.Methods:From January 2021 to September 2022,the clinical data of 120 patients with diabetic nephropathy admitted to our hospital were retrospectively collected and divided into the hypoglycemic and lipid-lowering group(56 cases)and the Bailing capsule group(64 cases)according to the treatment methods.The hypoglycemic and lipid-lowering group was treated with met-formin tablets and rosuvastatin calcium tablets.The bailing capsule group was treated with bailing capsules on the basis of the hypo-glycemic and lipid-lowering group.The curative effect after 3 months of treatment,glucose and lipid metabolism index,micro-inflamma-tory state and renal function before and after 3 months of treatment were compared between the two groups.Results:The therapeutic effect of the Bailing capsule group after 3 months was higher than that of the hypoglycemic and lipid-lowering group(P＜0.05).After 3 months of treatment,level of serum fasting blood glucose(FBG),glycated hemoglobin(HbA1c),total cholesterol(TC),triglyceride(TG),interleukin-6(IL-6),hypersensitive C-reactive protein(hs-CRP),serum levels of creatinine(SCr),urea nitrogen(BUN)and 24 h urinary albumin(24 h)in both groups UTP)and urinary albumin excretion rate(UAER)were lower than before treatment,and the Bailing cap-sule group was lower than the hypoglycemic and lipid-lowering group(P＜0.05).The level of serum interleukin-10(IL-10)in the two groups was higher than that before treatment,and that in the Bailing capsule group was higher than that in the hypoglycemic and lipid-lowering group(P＜0.05).Conclusion:Bailing capsule coyld effectively improve glucose and lipid metabolism,renal function and microinflammation in patients with diabetic nephropathy,with good curative effect.
Diabetic nephropathyBailing capsuleMetforminRosuvastatinMicroinflammatory stateRenal function
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