The Effect of Early Follicular Phase Long-acting Protocol Combined with Whole Process Recombinant Luteinizing Hormone on Ovulation and Pregnancy Outcomes of High Ovarian Response
Objective:To explore the effect of early follicular phase long-acting protocol combined with whole process recombi-nant luteinizing hormone(r-LH)on ovulation and pregnancy outcomes of high ovarian response.Methods:A total of 150 cases high ovarian response patients who underwent long-term ovulation induction in our hospital from January 2021 to March 2023 were divided into Matched group(r-LH was added,n=75)and observation group(r-LH was added,n=75 according to r-LH).Oovulation-related indicators and pregnancy outcomes were compared between the two groups.Results:Gn days,total Gn days,HCG daily serum LH level,and high-quality embryo rate were higher than that of the observation group,and the number of eggs obtained was less than that of the Matched group(P＜0.05).There was no difference between the days of reduction,Gn initiation,E2,P level,and endometrial thickness,clinical pregnancy rate,live birth rate,and abortion rate between the two groups(P＞0.05).Conclusion:The addition of r-LH significantly increased LH levels in vivo and improved the rate of high-quality follicles when ovulation was promoted in patients with ovarian hyperre-sponsiveness undergoing the early follicular phase of the long-acting,long-lasting regimen,which had an improved effect on pregnancy outcome.
High ovarian responseLong term rectangular planEarly follicular phaseRecombinant luteinizing hormoneOvula-tionPregnancy outcome
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