Characterization of the Distribution of Group B Streptococcal Infections in Pregnant Women in Late Pregnancy,Analysis of Risk Factors and Their Impact on Reproductive Tract Microbiology and Pregnancy Outcome
Objective:To analyze the characteristics of GBS infections in pregnant women in late pregnancy,associated factors,and their impact on reproductive tract microbiology,pregnancy outcomes.Methods:From June 2022 to June 2023,982 late-pregnant pregnant women admitted to Yubei People's Hospital in Chongqing who received vaginal secretion examination,according to GBS infec-tion,were divided into infected(98 cases)and uninfected(884 cases)groups.Factors influencing GBS infection in pregnant women in late pregnancy analyzed using univariate and Logistic regression,and the detection of genital tract microorganisms and pregnancy out-comes between the infected and uninfected groups were compared.Results:Age,body mass index(BMI),presence of preconception ex-amination,presence of combined gestational hypertension,presence of combined gestational diabetes mellitus,and presence of vaginal and cervical inflammation were statistically different between the infected group and the uninfected group(P＜0.05).Age ≥ 35 years,BMI ≥28 kg/m2,combined gestational hypertension,combined gestational diabetes mellitus,and the presence of vaginal and cervical inflammation were the independent risk factors(OR=2.477,3.077,4.586,3.540,and 2.942,P＜0.05);and that pre-pregnancy checkups were the protective factor(OR=0.465,P＜0.05).The detection rates of trichomonas,fungi,vaginosis and the incidence of premature rupture of membranes,intrauterine distress,neonatal pneumonia,and neonatal jaundice were higher in the infected group when compared to the uninfected group(P＜0.05).Conclusion:GBS infection in pregnant women in late pregnancy were associated with age ≥ 35 years,BMI≥28 kg/m2,comorbid gestational hypertension,comorbid gestational diabetes mellitus,presence of vaginal and cervical inflammation,and pre-pregnancy checkups,and GBS infection could affect the microenvironment of the reproductive tract and cause the development of adverse pregnancy outcomes.
Pregnant womenLate pregnancyGroup B streptococciRisk factorsMicrobiologyPregnancy outcome
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