Effects of Levosimendan on Myocardial Perfusion and Electrocardiogram Indexes in Patients with Acute Myocardial Infarction after PCI
Objective:To study Effects of levosimendan on myocardial perfusion and electrocardiogram indexes in patients with acute myocardial infarction after Percutaneous coronary intervention(PCI).Methods:113 patients with acute myocardial infarction who received PCI treatment in our hospital from January 2020 to December 2022 were selected and divided into experimental group(n=57)and control group(n=56)by random number table method.The control group was treated with clopidogrel after PCI,and the experimen-tal group was treated with levosimendan.The clinical efficacy,myocardial perfusion grade,ST segment retreat within 2 h,Tp-e/QT,CI,LVEF,LVESD,LVEDD and the incidence of complications were compared between the two groups.Results:The total effective rate of the experimental group was 89.13％,higher than that of the control group 71.1 1％(P＜0.05).After treatment,the myocardial perfusion grade level of both groups was increased,and the increase of experimental group was more obvious(P＜0.05).The ST segment in test group was better than that in control group within 2 h(P＜0.05).After treatment,the Tp-e/QT level in both groups was decreased,and the decrease in test group was more obvious(P＜0.05).After treatment,CI and LVEF levels were increased in both groups,more significantly in experimental group(P＜0.05);LVESD and LVEDD levels were decreased in both groups,more significantly in experimental group(P＜0.05);During treatment,the main adverse reactions were nausea,fever,recurrent angina pectoris and arrhythmia,and the incidence rate was compared between the two groups(P＞0.05).Conclusion:Levosimendan has a good effect in PCI treatment of patients with acute myocardial infarction,which can effectively improve the level of myocardial perfusion and electrocardiogram.
LevosimendanClopidogrelAcute myocardial infarctionPercutaneous coronary interventionMyocardial perfusionElectrocardiogram index
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