The Therapeutic Effect of Bacterial Dissolution Product Capsules on Children with Bronchial Asthma and Their Impact on Levels of Serum CRP,SAA,PCT,and FeNO
Objective:To explore the therapeutic effect of bacterial dissolution product capsules on children with bronchial asthma(BA)and their impact on levels of serum C-reactive protein(CRP),amyloid A(SAA),procalcitonin(PCT),and exhaled nitric oxide(FeNO).Methods:The research subjects were selected from children with BA who were treated in our hospital from December 2021 to July 2023.A total of 80 cases were included and divided into the group A and the group B,with 40 cases in each group.The grouping method was random number table method.Both groups were given routine symptomatic treatment,using inhaled budesonide suspension to treat the group A patients.On the basis of treatment for the group A patients,bacterial dissolution product capsules were used to treat the group B patients.The clinical efficacy,recovery progress,lower respiratory tract infection,upper respiratory tract infection,frequency of asthma attacks during treatment,lung function,levels of serum CRP,SAA,PCT,FeNO before and after 3 months of treatment,and evaluate the safety during treatment between two groups were compared.Results:After 3 months of treatment,the rate of total effective in the group B was 95.00％,which was higher than 77.50％of the group A(P＜0.05).Compared with the the group A,the relief and disap-pearance time of cough in the group B were shorter;During treatment,The frequency of lower respiratory tract infections,upper respira-tory tract infections,and asthma attacks in the group B were all lower than those in the group A(P＜0.05).Compared with before treat-ment,after 3 months of treatment,the lung function indicators of both groups increased,and compared with the the group A,the group B was higher(P＜0.05).Compared with before treatment,after 3 months of treatment,the levels of serum CRP,SAA,PCT,and FeNO in both groups decreased,and compared with the the group A,the group B was lower(P＜0.05).During the treatment period,there was no significant difference in the incidence of adverse reactions between the group B and the group A(22.50％vs 17.50％,P＞0.05).Conclu-sion:Bacterial dissolution product capsules could significantly promote the relief of asthma and respiratory infection symptoms in chil-dren with BA,improve lung function,alleviate inflammatory reactions in children,and thus improve treatment effectiveness with good safety.
Bronchial asthmaBacterial dissolution product capsulesC-reactive proteinStarch protein AProcalcitoninExhaled nitric oxide
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