Risk Factors for Severe Infection and Influencing Factors of Adverse Cardiovascular Events in Patients with Chronic Renal Failure and Uremia Undergoing Hemodialysis Maintenance Therapy
Objective:To explore the risk factors for severe infection and the influencing factors of adverse cardiovascular events in patients with chronic renal failure in the uremic stage undergoing hemodialysis maintenance therapy.Methods:Sixty patients with chronic renal failure and uremia admitted to our hospital from October 2021 to October 2023 were selected as the study subjects,and all patients received maintenance hemodialysis treatment.Group patients according to the number of severe infections and adverse cardio-vascular events.The infection group(n=20),non infection group(n=40),and adverse cardiovascular event group(n=22),non adverse cardiovascular event group(n=38).Analyze the general clinical situation of all patients,with severe infection and adverse cardiovascular events as dependent variables,and incorporate them into a logistic regression model to analyze the independent influencing factors of se-vere infection and adverse cardiovascular events.Results:There were significant differences in age,diabetes,dialysis time,heart failure,indwelling venous catheter,hemoglobin,Hs CRP,albumin and fasting blood glucose between the infected group and the non infected group(P＜0.05);Age,diabetes,indwelling venous catheter,Hs CRP and fasting blood glucose were independent risk factors for severe in-fection in patients with chronic renal failure in uremic stage undergoing hemodialysis maintenance treatment(P＜0.05);There were signif-icant differences in primary disease,hypertension,diabetes,hyperlipidemia,smoking history,hyperphosphatemia,dialysis time,Hs-CRP,LDL-C between the adverse cardiovascular event group and the non adverse cardiovascular event group(P＜0.05);Hypertension,hyper-lipidemia,hyperphosphatemia,Hs CRP,and dialysis time are independent risk factors for adverse cardiovascular events in patients with chronic renal failure in the uremic stage undergoing hemodialysis maintenance therapy(P＜0.05).Conclusion:Age,diabetes,indwelling venous catheter,Hs CRP,and fasting blood glucose are independent risk factors for severe infection in patients with chronic renal failure in uremic stage undergoing hemodialysis maintenance treatment.Hypertension,hyperlipidemia,hyperphosphatemia,Hs CRP,and dialy-sis time are independent risk factors for adverse cardiovascular events.
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