The Effect of Yixin Kangtai Capsule Combined with Betaloc in the Treatment of Coronary Heart Disease Angina Pectoris and Its Impact on Clinical Symptoms and Body Cytokines
Objective:To explore the therapeutic effect of Yixin Kangtai Capsules combined with Betaloc in the treatment of coronary heart disease angina pectoris,as well as its impact on clinical symptoms and body cytokines.Methods:80 CAD angina patients admitted from October 2020 to October 2023 were selected and divided into observation group and control group,40 patients each.The Matched group received treatment with Betaloc,while the observation group received treatment with Yixin Kangtai Capsules combined with Betaloc.The number and duration of angina attacks,changes in traditional Chinese medicine syndrome scores,neutrophil gelatinase associated lipoprotein(NGAL),cardiotrophin-1(CT-1),and interleukin-18(IL-18)were compared between the two groups of patients before and Post-treatment Leukotriene B4(LTB4),tissue transforming growth factor β Transforming growth factors within the organiza-tion β The changes in cytokines and hemorheological indicators related to the binding protein(LTBP-2)were evaluated,and the quality of life of the two groups of patients was evaluated using the Minnesota Heart Failure Quality of Life Questionnaire(MLHFQ).Results:Post-treatment:The clinical symptoms of the two groups improved,and the observation group improved greatly compared with the matched group(P＜0.05);Post-treatment,The cytokine levels were reduced in both groups,and the observation group was lower than the matched group(P＜0.05);Post-treatment,platelet aggregation rate,plasma viscosity,whole blood low shear,and whole blood high shear levels were significantly reduced in both groups of patients,and the observation group was lower than the matched group(P＜0.05);Post-treatment,the MLHFQ scores of the two groups of patients increased,and the observation group was higher than the matched group(P＜0.05).Conclusion:For patients with coronary heart disease and angina pectoris,Yixin Kangtai capsule combined with betalk can re-duce the number of angina attacks,shorten the duration of angina pectoris,reduce the clinical symptoms of patients,improve the cytokine expression level of patients,reduce blood viscosity,and improve the quality of life of patients.
Yixin Kangtai CapsulesBetalocCoronary heart diseaseAngina pectorisClinical symptomsCytokinesQuality of Life
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