The Application Effect of Posterior Continuous Intermuscular Groove Brachial Plexus Block Combined with Parexib Sodium for Preemptive Analgesia in Patients Undergoing Shoulder Arthroscopic Surgery
Objective:To explore the application effect of posterior continuous intermuscular groove brachial plexus block com-bined with parecoxib sodium preemptive analgesia on patients undergoing shoulder arthroscopic surgery.Methods:80 patients who un-derwent shoulder arthroscopic surgery from January 2020 to January 2023 were selected.They were randomly divided into three groups:A,B,and C,with 25 cases in Group A,25 cases in Group B,and 30 cases in Group C.Group A received routine intravenous anesthesia,Group B received routine intravenous anesthesia combined with posterior continuous intermuscular sulcus brachial plexus block group,and Group C received posterior continuous intermuscular sulcus brachial plexus block combined with parecoxib sodium for preemptive analgesia.Compare the changes in heart rate,blood oxygen,and blood pressure levels,as well as changes in stress response indicators related to cortisol(COR)and norepinephrine(NE),among the three groups of patients at entry(T1),10 minutes of surgery(T2),30 minutes of surgery(T3),and immediately after surgery(T4).Compare the incidence of adverse reactions among the three groups of patients.Finally,conduct a 6-month outpatient follow-up for all patients,at preoperative and postoperative 1 month and 3 months,respectively The Con-stant Murley score was used to evaluate the shoulder joint function of three groups of patients at 6 months.Results:There was no differ-ence in heart rate,blood oxygen saturation,systolic and diastolic blood pressure among the three groups of patients at T1 and T4 time(P＞0.05).The heart rate,blood oxygen saturation,systolic and diastolic blood pressure levels of Group C were lower than those of Group A and Group B at T2 and T3 time(P＜0.05),and the T,to T4 time was relatively stable;There was no difference in the expression levels of COR and NE among the three groups of patients at T1 time(P＞0.05),while the expression levels of COR and NE were increased in the three groups at T2 and T3 time.Moreover,the expression levels of COR and NE in Group C were lower than those in Group A and Group B at T2,T3,and T4 time(P＜0.05);There was no difference in the incidence of adverse reactions among patients in groups A,B and C(P＞0.05);There was no difference in the preoperative Constant Murley scores among the three groups of patients.After 1 month,3 months,and 6 months of surgery,the Constant Murley scores of the three groups of patients all increased,and Group C was significantly higher than Group A and Group B(P＜0.05).Conclusion:For patients undergoing shoulder arthroscopic surgery,the combination of poste-rior continuous intermuscular groove brachial plexus block group and Parexib sodium for preemptive analgesia can stabilize intraopera-tive blood oxygen saturation,heart rate,and blood pressure levels,reduce intraoperative stress response,and have high safety.At the same time,it can further assist patients in improving long-term shoulder joint function.
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