Analysis of Risk Factors of Portal Vein Thrombosis and Endoscopic Treatment of Backdoor Hypertension Gastric Aggravation in Patients with Esophageal and Gastric Varices
Objective:To explore the risk factors of portal vein thrombosis and treatment of backdoor hypertension in patients with esophageal and gastric varices.Methods:In tively,102 patients from January 2019,all patients underwent endoscopic treatment with oesophageal and gastric varices,with portal venous thrombosis group(n=48 cases)and non-portal vein thrombosis(54 cases),compared with the two groups of laboratory examination,general clinical data,imaging examination results,and multifactor Logistic regression analysis was used to determine the risk factors of esophageal and gastric venous thrombosis.According to whether the patient has portal hypertension gastric disease aggravation after treatment.102 patients were divided into portal hypertension plus restructuring and no portal hypertension and aggravation,and the general data and laboratory examination results of the two groups were compared.Multivariate Logistic regression analysis identified the risk factors for endoscopic treatment of posterior artery hypertension gastric disease aggravation.Results:The proportion of endoscopic esophageal varicose portal vein thrombosis was 47.06％(48/102).Univariate analysis showed that splenectomy history of portal vein thrombosis,gastric sclerosis injection,PLT,FIB,D2,internal diameter of portal vein,spleen length,spleen thickness,and splenic vein diameter without portal vein thrombosis(P＜0.05);multifactor Logistic regression analysis showed that the history of splenectomy,D-dimer,PLT,splenic thickness,and enlarged splenic vein diameter were the risk factors for portal vein thrombosis in patients with cirrhosis(P＜0.05).The proportion of endoscopic treatment for backdoor hypertension gastric disease aggravation was 29.41％(30/102).The results of the univariate analysis showed that,Portal hypertensive gastric disease and esophageal gastric Pux grade,Child-Pugh grade,Hp infection,portal vein flow history,portal vein trunk diameter and splenic vein diameter(P＜0.05);The multivariate Logistic regression analysis showed that,Severe esophageal varicose veins,Child-Pugh grade C,Hp infection,and history of portal vein disconnection were the risk factors for endoscopic treatment of posterior artery hypertension in cirrhosis(P＜0.05).Conclusion:A history of splenectomy,D-dimer,PLT,splenic thickness,and elevated splenic vein diameter are the risk factors for portal vein thrombosis of esophageal and gastric varices,severe,Child-Pugh grade C,Hp infection,and a history of portal vein rupture are the risk factors for the aggravation of portal hypertensive gastric disease after endoscopic treatment of liver cirrhosis.
Esophageal varices in cirrhosisPortal vein thrombosisEndoscopic treatment of oesophageal and gastric varicesPortal hypertensive gastropathy aggravatedRisk factor
NETL
NSTL
万方数据
