The Effect of Activating Blood Circulation and Removing Stasis Combined with Thymic Method Based on Yishen Huayu Tang on Renal Interstitial Damage and Immune Regulation after Chemotherapy in Advanced Cervical Cancer
Objective:To explore the effect of the combination of activating blood circulation and removing stasis with thymic method based on Yishen Huayu Tang on renal interstitial damage after chemotherapy in advanced cervical cancer and its immunomodulatory effect.Method:80 patients with renal interstitial damage after chemotherapy for advanced cervical cancer admitted to our hospital from October 2020 to October 2023 were selected.They were divided into an observation group and a control group,with 40 cases.All patients were treated with platinum containing chemotherapy,while the control group was treated with thymic method.The observation group was treated with Yishen Huayu Tang combined with thymic method.The changes in renal function indicators and immune function before and Post-treatment were compared between the two groups,and the incidence of chemotherapy adverse reactions was compared between the two groups,Finally,the quality of life of the two groups of patients was evaluated using the WHO QOL-100 before and Post-treatment.Result:Post-treatment,the levels of SCr,BUN,β2-MG,and CysC were decreased in the observation group was lower than that in the control group(P＜0.05);Post-treatment,the CD4+,CD3+,and CD4+/CD8+values,IgM,IgG,and IgA levels of the two groups of patients decreased,and the observation group was higher than the control group(P＜0.05);The incidence of chemotherapy adverse reactions related to heart function impairment,liver function impairment,fever,gastrointestinal reactions,decreased hemoglobin,thrombocytopenia,and bone marrow suppression in the observation group was lower than that in the control group(P＜0.05);Post-treatment,the WHOQOL-100 related scores of both groups of patients increased,and the observation group was higher than the control group(P＜0.05).Conclusion:The combination of Huoxue Huayu and thymus therapy based on Yishen Huayu Tang can improve the renal function of patients with renal interstitial damage after chemotherapy for advanced cervical cancer,and can produce immune regulatory effects,improve patient immune function,reduce the incidence of other chemotherapy adverse reactions,and enhance patient quality of life.
Yishen Huayu TangPromoting blood circulation and removing blood stasisNew thymic methodCervical cancerRenal interstitial damageImmune functionRenal function
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