Analysis of the Application Effect of Closed Thoracic Drainage Tube Combined with High-frequency Oscillatory Ventilation on Neonatal Meconium Aspiration Syndrome Complicated with Respiratory Failure
Objective:To explore the application effect of closed thoracic drainage tube combined with high-frequency oscillatory ventilation on neonatal meconium aspiration syndrome with respiratory failure.Methods:Sixty newborns with meconium aspiration syndrome and respiratory failure admitted to our hospital from January 2018 to January 2024 were selected.They were divided into an observation group and a matched group,with 30 cases.Children in the matched group adopted conventional mechanical ventilation and chest closed drainage,and children in the children in the observation group adopted chest closed drainage tube combined with high-frequency oscillatory ventilation to compare relevant indicators.Results:The total response rate in the observation group was high compared with the matched group(P＜0.05);Before treatment,there was no significant difference in the pH value,PaCO2,SaO2,and PaO2 levels between the two groups of children(P＞0.05).Post-treatment,PaCO2 decreased,and pH,SaO2 and PaO2 increased in the two groups,with the same trend compared with the control group(P＜0.05);There was no difference in MAP and HR between the two groups of children before and Post-treatment(P＞0.05);There was no difference in the incidence of complications between the two groups of children(P＞0.05);Before treatment,there was no difference in MAP and HR between the two groups of children(P＞0.05).Post-treatment,the MAP of the two groups of children increased,and the observation group was higher than the matched group,while HR decreased.The observation group was higher than the matched group(P＜0.05);There was no difference in the incidence of complications between the two groups of children(P＞0.05).Conclusion:For newborns with meconium aspiration syndrome combined with respiratory failure and pneumothorax,the use of closed thoracic drainage combined with high-frequency oscillatory ventilation can improve clinical efficacy,improve blood gas indicators,stabilize vital signs,and have high safety.
Closed thoracic drainageHigh frequency oscillation ventilationNeonatal meconium aspiration syndromeRespiratory failure
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