Comparative Study on the Analgesic Effect of Ultrasound-Guided Quadratus Lumborum Block Combined with Oxycodone in Different Approaches after Laparoscopic Colorectal-Carcinoma Surgey
Objective:To compare the analgesic effect of ultrasound-guided quadratus lumborum block(QLB)combined with oxycodone in different approaches after laparoscopic colorectal-carcinoma surgey(LCS).Methods:According to the random number table method,148 patients who underwent LCS in our hospital from April 2021 to March 2023 were divided into group A,group B and group C,with 49 cases,49 cases and 50 cases respectively.Group A received oxycodone,group B received posterior QLB combine with oxycodone,and group C received anterior quadratus lumborum block on lateral arcuate ligament(QLB-LSAL)combine with oxycodone.The number of remedial analgesia cases at 48 h after operation,the effective pressing times of patient-controlled intravenous analgesia(PICA),the visual analogue scale(VAS)scores at rest and cough,the quality of awakening,the stress response indexes[cortisol(Cor),epinephrine(E),norepinephrine(NE)]and the incidence of adverse reactions were compared among three groups.Results:The number of remedial analgesia cases in group A,group B and group C decreased in turn at 48 h after operation(P＜0.05).The effective pressing times of PICA in group A,group B and group C decreased in turn(P＜0.05).The recovery time,the first time to get out of bed,and the hospital stay after operation in group A,group B,and group C were shortened in turn(P＜0.05).The VAS scores in group A,group B and group C at rest and cough decreased in turn at 12 h,24 h and 48 h after operation(P＜0.05).1 d after operation,Cor,E and NE in group A,group B and group C decreased in turn(P＜0.05).There was no difference in the incidence of adverse reactions among three groups(P＞0.05).Conclusion:Ultrasound-guided QLB-LSAL combined with oxycodone has a significant analgesic effect after LCS,which can reduce the body's stress response and promote recovery after operation.
Different approachesQuadratus lumborum blockOxycodoneLaparoscopic colorectal-carcinoma surgeyAnalgesic effect
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