Application Value of MRI Multi-sequence Scan in the Diagnosis of Hepatocellular Carcinoma and Evaluation of Microvascular Invasion
Objective:To explore the application value of magnetic resonance imaging(MRI)multi-sequence scan in the diagnosis of hepatocellular carcinoma(HCC)and evaluation of microvascular invasion(MVI).Methods:A retrospective collection was performed on the clinical data of 100 patients with suspected HCC in the hospital between October 2019 and October 2022.All completed MRI multi-sequence scan and pathological examination.Taking pathological examination as the golden standard,the consistency between MRI multi-sequcnce scan and pathological examination in the diagnosis of HCC and evaluation of MVI was analyzed by Kappa test.Results:Among the 100 patients,pathological examination showed that there were 51 cases(51.00％)with HCC and 49 cases(49.00％)with benign liver lesions.In the 51 HCC patients,there were 17 cases(33.33％)with MVI.Taking pathological examination as the golden standard,sensitivity,specificity and Kappa values of T2WI in the diagnosis of HCC and MVI were(82.35％,79.59％,0.620)and(64.71％,85.29％,0.507),respectively.The sensitivity,specificity and Kappa values of T1WI in the diagnosis of HCC and MVI were(76.47％,81.63％,0.580)and(58.82％,88.24％,0.492),respectively.The sensitivity,specificity and Kappa values of LAVA in the diagnosis of HCC and MVI were(84.31％,83.67％,0.580)and(64.71％,91.18％,0.585),respectively.The sensitivity,specificity and Kappa values of MRI multi-sequence scan in the diagnosis of HCC and MVI were(96.08％,79.59％,0.759)and(94.12％,82.35％,0.712),respectively.The sensitivity of MRI multi-sequence scan was higher than that of single sequence(P＜0.05).The proportions of unsmooth tumor edge and peritumoral enhancement in patients with MVI positive were higher than those with MVI negative(P＜0.05).Conclusion:MRI multi-sequence scan is conductive to clinical diagnosis of HCC and evaluation of MVI.Unsmooth tumor edge and peritumoral enhancement have predictive significance in HCC and MVI.
Magnetic resonance imagingMulti-sequence scanHepatocellular carcinomaMicrovascular invasionDiagnosisConsistency
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