Relationship between CD64 Index,Systemic Immune Inflammation Index,CRP/Alb Ratio and Postoperative Infection in Patients with Partial Hepatectomy for Liver Cancer
Objective:To investigate the relationship between cluster of differentiation 64(CD64)index,systemic immune inflammation index(SII),C-reactive protein/albumin(CRP/Alb)ratio and postoperative infection in patients with partial hepatectomy(PR)for liver cancer.Methods:300 patients with liver cancer who underwent PR in our hospital from January 2021 to October 2023 were selected and divided into infection group and non-infection group according to whether postoperative infection occurred,the CD64 index,SII and CRP/Alb ratio were calculated.The factors of postoperative infection in patients with liver cancer PR were analyzed by multivariate Logistic regression analysis,the predictive value of CD64 index,SII and CRP/Alb ratio for postoperative infection in patients with liver cancer PR were analyzed by receiver operating characteristic(ROC)curve.Results:The incidence of postoperative infection in 300 patients with liver cancer PR was 21.33％(64/300).Compared with non-infected group,the CD64 index,SII and CRP/Alb ratio in infected group increased(P＜0.05).Multivariate Logistic regression analysis showed that diabetes mellitus,intraoperative blood transfusion,drainage tube placement time ≥ 7 d and elevated CD64 index,SII,CRP/Alb ratio were independent risk factors for postoperative infection in patients with liver cancer PR(P＜0.05).The area under the curve of CD64 index,SII and CRP/Alb ratio in predicting postoperative infection of PR patients with liver cancer was 0.910,which was greater than 0.790,0.778 and 0.776 predicted by CD64 index,SII and CRP/Alb ratio alone(P＜0.05).Conclusions:The increase of CD64 index,SII and CRP/Alb ratio are independent risk factor for postoperative infection in PR patients with liver cancer,the combination of CD64 index,SII and CRP/Alb ratio has higher value in predicting postoperative infection in PR patients with liver cancer.
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