Analysis of the Efficacy and Long-term Prognostic Risk Factors of Intracoronary Urokinase Thrombolysis for Acute Myocardial Infarction
Objective:To investigate the effect of intracoronary urokininogen thrombolysis in acute myocardial infarction and its long-term prognosis risk factors.Methods:200 patients with acute myocardial infarction admitted to 2020.3-2022.3 were treated with internal coronary urokininogen thrombolysis to compare the efficacy index.After 2 years of follow-up,38 patients who had adverse cardiovascular events were classified in the poor prognosis group,and the remaining 162 patients were in the good prognosis group to analyze long-term prognosis risk factors.Results:The recanalization rate was 95.00%,with 81.00%complete recanalization;and no severe brain hemorrhage during treatment,mild bleeding rate 6.00%;heart failure rate 6.50%,no cardiac death.After follow-up after 2 years,the incidence of long-term cardiovascular adverse events was 19.00%;age,onset to thrombolytic therapy,diabetes,hyperlipidemia,hypertension,NYHA,smoking history,coronary lesions,infarction and ischemic range(P<0.05);age,onset to thrombolytic therapy,NYHA cardiac function grade,coronary,infarction,and ischemic range were classified as independent risk factors for long-term prognosis(P<0.05).Conclusion:However,the long-term prognosis is affected by many factors,on high-risk patients.
Acute myocardial infarctionProurokinaseCoronary thrombolysisInfluencing factorsCardiovascular adverse eventsLong term prognosis