Effects of Yiqi Tongfu Decoction Combined with Ulinastatin on Gastrointestinal Hormones,Intestinal Flora and Intestinal Barrier Markers in Patients with Sepsis Gastrointestinal Dysfunction
Objective:To observe the effects of yiqi tongfu decoction combined with ulinastatin on patients with sepsis gastrointestinal dysfunction.Methods:98 patients with sepsis gastrointestinal dysfunction were divided into control group(treated with ulinastatin)and treatment group(treated with yiqi tongfu decoction on the basis of control group)according to the random number table method,49 cases in each group.The gastrointestinal hormones[motilin(MOT),gastrin(GAS)],intestinal flora[Bifidobacterium,Lactobacillus,Enterobacter,Enterococcus,Bacteroides]and intestinal barrier markers[diamine oxidase(DAO)and D lactic acid]were compared between two groups.Results:After treatment,compared with control group,DAO,D lactic acid,GAS level,Enterobacter,Enterococcus,and Bacteroides colonies in treatment group decreased,while the MOT level,Bifidobacterium,and Lactobacillus colonies increased(P＜0.05).Conclusion:Yiqi tongfu decoction combined with ulinastatin may improve the levels of intestinal flora,gastrointestinal hormones and intestinal barrier markers in patients with septic gastrointestinal dysfunction.
NETL
NSTL
万方数据
