Effect of 0.05％Cyclosporine Eye Drops(Ⅱ)on Dry Eye Symptoms and Tear Film Stability after FS-LASIK
Objective:To observe the effect of perioperative application of 0.05％cyclosporine(CsA)eye drops(Ⅱ)on dry eye symptoms and tear film stability after femtosecond laser-assisted laser in situ keratomileusis(FS-LASIK).Methods:92 patients who underwent FS-LASIK surgery and had dry eye symptoms after surgery were divided into 36 patients who used 0.05％CsA eye drops before operation(group A),32 patients who used 0.05％CsA eye drops 1 week after operation(group B),and 24 patients who did not use 0.05％CsA eye drops(group C).The Chinese dry eye questionnaire score,tear film rupture time(BUT),corneal fluorescein staining(FL),conjunctival lissamine green staining(LG),and tear secretion test(SIt)were compared among three groups.Results:The Chinese dry eye questionnaire score,FL and LG in group B and group C were higher than those in group A at 1 week,1 month and 3 months after operation,and those in group C were higher than those in group B(P＜0.05).BUT and Sit in group B and group C were lower than those in group A at 1 week,1 month and 3 months after operation,and those in group C were lower than those in group B(P＜0.05).Conclusion:The use of 0.05％CsA eye drops(Ⅱ)before FS-LASIK can effectively alleviate the symptoms of dry eye,and improve the stability of tear film.
Femtosecond laser-assisted laser in situ keratomileusisisCyclosporine eye dropsDry eye symptomsTear film stability
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