Differences in Serum SUA,Thyroid Hormone Levels,and Inflammation Levels among Patients with Hyperuricemia of Different Genders and Their Correlation with Disease Severity
Objective:Study differences in serum uric acid(SUA),thyroid hormones,and inflammatory markers between genders in hyperuricemia patients,and analyze their correlation with disease severity.Methods:100 hyperuricemia patients(2021-2023)were grouped by gender(male:57,female:43).Compared relevant indicators between groups.Patients were further stratified by severity(mild:33,moderate:45,severe:22)to analyze SUA,thyroid hormones,inflammation,and their correlation with severity.Results:Males had higher gouty arthritis and tophus rates,while females had more asymptomatic hyperuricemia(P＜0.05).Males had higher IL-6,TNF-α,and hs-CRP levels(P＜0.05).SUA,TSH,and inflammatory markers increased with severity,while FT3 and FT4 decreased(P＜0.05).Spearman analysis showed SUA,TSH,IL-6,TNF-α,hs-CRP positively correlated,and FT3,FT4 negatively correlated with severity(P＜0.05).Conclusion:Gender differences impact hyperuricemia manifestations and inflammation.SUA,thyroid hormones,and inflammation are closely related to disease severity.
GenderHyperuricemiaBlood uric acidThyroid hormoneInflammatory factorsThe severity of the diseaseRelativity
NETL
NSTL
万方数据
